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Human Biology News
June 26, 2022

Top Headlines
 

Lipid Nanoparticles Carry Gene-Editing Cancer Drugs Past Tumor Defenses

As they grow, solid tumors surround themselves with a thick, hard-to-penetrate wall of molecular defenses. Getting drugs past that barricade is notoriously difficult. Now, scientists have developed ...

Many Human Genomes Shaped by Past Events That Caused Sharp Dips in the Population, Study Finds

The genomes of many human populations show evidence of founder events, which occur when a small number of initial members start a new population, and ...

New Technology Helps Reveal Inner Workings of Human Genome

Researchers have developed a new method to assess on a large scale the three-dimensional structure of the human genome, or how the genome folds. The genome is the complete set of genetic ...

Hair-Raising Research: Scientists Find Surprising Link Between Immune System, Hair Growth

Scientists have uncovered an unexpected molecular target of a common treatment for alopecia, a condition in which a person's immune system attacks ...
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ALS May Be Linked to Both the Immune and Central Nervous Systems

The immune system may play a fundamental role along with the central nervous system in amyotrophic lateral sclerosis (ALS), also known as 'Lou Gehrig's disease,' researchers ...

Muscle Biopsy Test for Biomarker Could Lead to Earlier Diagnosis of ALS

Amyotrophic lateral sclerosis (ALS) is a progressive disease of the nervous system. It affects nerve cells in the brain and spinal cord called motor neurons. Motor neurons control muscle movement and ...

Scientists Unravel Genetic Mystery of Rare Neurodevelopmental Disorder, Provide Definitive Diagnoses to 21 Families Worldwide

Scientists have discovered 15 additional genetic mutations in the KCNK9 gene that cause a neurodevelopmental syndrome. Symptoms of the disorder range from speech and motor impairment to behavioral ...

Vital Cell Machinery Behind the Human Body's Incorporation of Selenium Observed

Scientists have determined the process for incorporating selenium -- an essential trace mineral found in soil, water and some foods that increases antioxidant effects in the body -- to 25 specialized ...

Lack of Diversity of Micro-Organisms in the Gut or Elevated Metabolite Implicated in Heart Failure Severity

Some people who experience heart failure have less biodiversity in their gut or have elevated gut metabolites, both of which are associated with more hospital visits and greater risk of death, ...

New Model Helps Identify Mutations That Drive Cancer

Scientists built a computer model that can rapidly scan the entire genome of cancer cells and identify mutations that occur more frequently than expected, suggesting that they are driving tumor ...

Diversity of Centrosomes Delivers New Clues for Neurological Diseases

A neurobiologist is pursuing important leads in her quest to elucidate the causes of neurological diseases. Together with her team, she has gained new insights into the human centrosome, whose ...

Gene Discovery Indicates Motor Neuron Diseases Caused by Abnormal Lipid Processing in Cells

A new genetic discovery adds weight to a theory that motor neuron degenerative diseases are caused by abnormal lipid (fat) processing pathways inside brain cells. This theory will help pave the way ...

More Than One Way to Skin a Tumor

The mechanism by which active inflammation occurs in parallel with immunosuppression in the tumor microenvironment has been identified. Results showed reduced gene expression of regulatory T cell ...

Biochemistry Researchers Repair and Regenerate Heart Muscle Cells

Researchers are reporting new technology that not only repairs heart muscle cells in mice but also regenerates them following a heart attack, or myocardial infarction as its medically ...

Scientists Unravel the Mystery of Genes That Are Key to Brain Development

New research shows the mechanism by which genes coding for a subset of long non-coding RNA (lncRNA) interact with neighboring genes to regulate the development and function of essential nerve ...

Drilling for Rare Disease Therapeutics

A drug discovery approach developed -- in part inspired by oil companies -- revealed why drugs for cystic fibrosis fall ...

Molecular 3D-Maps Unlock New Ways of Studying Human Reproduction

Scientists have identified the biochemical signals that control the emergence of the body pattern in the primate embryo. This will guide work to understand birth defects and pregnancy loss in ...

Mechanism Leading to Drug Resistance in Prostate Cancer

Researchers reveal a mechanism by which prostate cancer cells become resistant through molecular modification of the androgen receptor protein and identify a potential treatment approach that could ...

New Perspective on RNA Function: RNA Regulates Proteins and Thereby Can Control Cell Growth, Study Shows

Scientists gained new insights into RNA-mediated regulation of proteins (riboregulation) and its role in controlling cell growth, and most importantly how undifferentiated cells (embryonic stem ...

Tumor 'Signatures' Could Provide Key to More Accurate Treatment for Deadliest Cancers

Scientists have found a way to identify and interpret 'signatures' that reveal the complex genetic causes of some of the deadliest cancers -- which often have a survival rate of less than ...

A Dynamic Duo of Cells Identified in Lung Blood Vessels

Scientists have identified two subtypes of lung blood vessel cells. One subtype expresses more genes involved in inflammation and the regulation of the immune response; the other expresses more genes ...

Study Reveals How Epilepsy and Migraine Drug Causes Birth Defects

Valproic acid -- a drug used to treat epilepsy, migraine, and bipolar disorder -- can cause birth defects when taken during pregnancy. Now, a study reveals one reason why: valproic acid (VPA) puts ...

DNA Nanotech Safe for Medical Use, New Study Suggests

Advances in nanotechnology have made it possible to fabricate structures out of DNA for use in biomedical applications like delivering drugs or creating vaccines, but new research in mice ...

New Research Identifies More Than 1,000 Genes Linked to Severe COVID-19

A new study reveals why some healthy adults with the COVID-19 infection become seriously ill, while others have few ...

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