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Lymphoma News
June 28, 2022

Top Headlines
 

The Interferon Gamma Receptor Pathway Is Necessary for CAR T-Cell Mediated Killing in Solid Tumors

Researchers have discovered that the interferon gamma receptor (IFNgR) signaling pathway is critical for susceptibility of glioblastoma tumors to ...

Early Study Finds New Lymphoma Drug Effective

In early research, the oral medication zanubrutinib was found to help most patients with a slow-growing type of cancer known as marginal zone ...

CRISPR-Edited CAR T Cells Enhance Fight Against Blood Cancers

Knocking out a protein known to stifle T cell activation on CAR T cells using the CRISPR/Cas9 technology enhanced the engineered T cells' ability to eliminate blood ...

Breakthrough With Cancer Vaccine

Scientists have developed a new cancer vaccine with the potential to activate the body's immune system to fight a range of cancers, including leukaemia, breast cancer, lung cancer and pancreatic ...
Latest Headlines
updated 4:59pm EDT

Earlier Headlines
 

Ibrutinib With Chemoimmunotherapy Improved Progression-Free Survival for Newly Diagnosed Mantle Cell Lymphoma Patients

Combination chemoimmunotherapy with the Bruton's tyrosine kinase (BTK) inhibitor ibrutinib demonstrated improved progression-free survival over standard chemoimmunotherapy for previously ...

Researchers Seek to Improve Success of Chimeric Antigen Receptor-T Cell Therapy in Non-Hodgkin Lymphoma

A study investigates the reasons for decreasing remission rates for patients with non-Hodgkin lymphoma treated with chimeric antigen receptor-T cell therapy (CAR-T cell ...

All Cells Are Important: A Roadmap to Characterize Lymphoma Stroma

Researchers identify gene expression signatures in different types of lymph nodes cells that play an active role in the development of ...

Key Genomic Alterations and Potential Therapeutic Vulnerabilities in Transformed Cutaneous T-Cell Lymphoma

Researchers have shared a comprehensive multiomics study from a rare cohort of 56 patients with transformed CTCL and identified several genomic alterations and oncogenic programs that may be ...

Lymphoma: Key Signaling Pathway Involved in Tumor Formation Identified

There are myriad reasons why cancers develop. By studying genes which are altered in people with lymphoma, a multidisciplinary team of researchers has identified a key mechanism involved in disease ...

Lymphoma Cell Metabolism May Provide New Cancer Target

Aggressive and relatively common lymphomas called diffuse large B cell lymphomas (DLBCLs) have a critical metabolic vulnerability that can be exploited to trick these cancers into starving ...

Scientists Discover a Fundamental Feature of Aggressive Lymphomas

New research has revealed a new fundamental feature of aggressive B-cell lymphomas which could open the door to further research into early detection and treatment of the ...

Study Finds 94 Percent of Patients With Cancer Respond Well to COVID-19 Vaccines

More than 9 of 10 patients with cancer showed good immune response to the COVID-19 mRNA vaccines after receiving both doses, but subsets of high-risk patients did not, according to a new ...

New CAR T Approach Minimizes Resistance, Helps Avoid Relapse in Non-Hodgkin's B-Cell Lymphoma

Early results from a new, pioneering chimeric antigen receptor (CAR) T cell immunotherapy trial found using a bilateral attack achieves a more robust defense and helps avoid ...

Scientists Unlock Promising Key to Preventing Cancer Relapse After Immunotherapy

The researchers discovered that cancer immunotherapies that make use of immune system cells such as T cells and CAR-T cells kill not only tumor cells that express the drugs' target, but also ...

Potential Treatment Approach Kills Lymphoma While Sparing Healthy Cells

Scientists at Scripps Research have demonstrated a promising new strategy for treating lymphomas, a group of cancers that begin in infection-fighting cells of the immune system called ...

CAR T-Cell Therapy Found Highly Effective in Patients With High-Risk Non-Hodgkin Lymphoma

A CAR T-cell therapy known as axicabtagene ciloleucel (axi-cel) drove cancer cells to undetectable levels in nearly 80% of patients with advanced non-Hodgkin lymphoma (NHL) in a phase 2 clinical ...

Novel Therapeutic Approach Against Epstein-Barr Virus-Associated Tumors

A research team hsd discovered that certain exosomes can effectively control Epstein-Barr virus-associated tumors and induce T-cell anti-tumor immunity. The novel findings provide insights into new ...

Memory Training for the Immune System

The immune system will memorize the pathogen after an infection and can therefore react promptly after reinfection with the same pathogen. Now, scientists have deciphered new details of this ...

Acidic Niche Keeps Lymphatic System in Check During Immune Response

Researchers describe a novel acidic niche within lymph nodes that plays an integral role in regulating T cell ...

The Fight Goes On: Clinical Trial Shows Promising New Treatment for Rare Blood Cancer

Although lymphoma is one of the most common types of blood cancer, it has a rare subtype for which no effective treatment regimens are known. For the first time, researchers have conducted clinical ...

Novel Antiviral Targeted Drug for Nasopharyngeal Cancer

A research team has developed a novel anti-Epstein-Barr virus (EBV) drug that can selectively disrupt a viral protein produced by EBV, leading to the shrinkage of tumors caused by the virus. It is ...

Lymphatic Vessels in Mice and Humans: Alike Yet Different

In an international collaboration, researchers have mapped the lymph node lymphatic vessels in mice and humans down to the level of individual cells. The results may eventually help scientists to ...

A New Therapeutic Target Turns the Immune System Against Lymphoma

Scientists have identified a key mechanism that tumor cells use to take advantage of and avoid detection from the immune system. Targeting this mechanism offers a new therapeutic strategy for cancers ...

New Front Opened in Fight Against Common Cancer Driver

Researchers have revealed a new vulnerability in lymphomas that are driven by one of the most common cancer-causing changes in cells. The team hopes that this could be a new target for treating a ...

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