Pharmaceuticals News
June 26, 2022

Top Headlines

Promising Rectal Cancer Study

A scientist comments on the evolving treatment of rectal cancer in light of findings from a study that found the immunotherapy drug dostarlimab was especially effective in a phase II clinical trial ...

This Parasite Will Self-Destruct: Researchers Discover New Weapon Against Drug-Resistant Malaria

A new method to combat malaria which sees the disease turn against itself could offer an effective treatment for the hundreds of millions of people ...

Combination Anti-HIV Antibody Infusions Suppress Virus for Prolonged Period

Individuals with HIV who began taking antiretroviral therapy (ART) in the early stages of infection achieved a lengthy period of HIV suppression without ART after receiving two broadly neutralizing ...

New Type of Triterpenes Discovered

A remarkable discovery and collaborative effort have revealed a new type of triterpenes, a group of organic compounds which are an important source of many medicines. Until now, all triterpenes were ...
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Earlier Headlines

Mechanism Leading to Drug Resistance in Prostate Cancer

Researchers reveal a mechanism by which prostate cancer cells become resistant through molecular modification of the androgen receptor protein and identify a potential treatment approach that could ...

Targeted Drug Achieves 43% Response Rate in KRAS-Mutated Lung Cancer

Nearly 43% of patients with non-small cell lung cancer (NSCLC) whose lung cancers harbored a specific KRAS mutation responded to the experimental drug adagrasib, and the targeted agent also showed ...

Novel Approach Identifies Highly Specific Anti-Cancer Compounds

Researchers have identified potent, highly specific compounds that interfere with bromodomain (BD)-containing proteins involved in cancer. The compounds, called BET BD1-inhibitors, are a starting ...

A New Data-Driven Model Could Provide a Powerful Policy Planning Tool to Combat the Nation's Opioid Crisis

A team of public health modelers and substance use experts has developed a dynamic model based on national data from 1999 to 2020 that tracks the evolution of the opioid crisis for public policy ...

Ibrutinib With Chemoimmunotherapy Improved Progression-Free Survival for Newly Diagnosed Mantle Cell Lymphoma Patients

Combination chemoimmunotherapy with the Bruton's tyrosine kinase (BTK) inhibitor ibrutinib demonstrated improved progression-free survival over standard chemoimmunotherapy for previously ...

Target Protein for Diabetes Drug Linked to Reduced Risk of Alzheimer's Disease

Mechanisms associated with a particular diabetes drug can also help to protect against Alzheimer's disease, a new study reports. The results indicate that the drug's target protein can be ...

Salmonella Vaccine for Poultry Contributed to Rise of Antibiotic-Resistant Bacteria, Researchers Report

An investigation into the evolution of Salmonella bacteria infecting Brazilian poultry shows that the introduction of a Salmonella vaccine, combined with increasing antibiotic usage by Brazilian ...

New Antibiotics Could Tackle Drug-Resistant Tuberculosis Bacteria

According to a new study, a new class of antibiotics is highly effective against drug-resistant tuberculosis. If validated in clinical trials, the new drug class would represent a major advance in ...

A Synthetic Antibiotic May Help Turn the Tide Against Drug-Resistant Pathogens

A synthesized antibiotic derived from computer models of bacterial gene products appears to neutralize even drug-resistant bacteria. The compound, named cilagicin, works well in mice and employs a ...

Gut Bacteria Can Make Blood Pressure Medication Less Effective

Hypertension, or high blood pressure, is a major risk factor for heart disease and stroke, two of the leading causes of death in America. It's also one of the most common chronic conditions in ...

More Young People Begin Recreational Cannabis Use Illegally in States That Legalize It

Once a state legalizes recreational cannabis and increase in youth using it illegally occurs, report ...

Cryogenic Electron Microscopy Reveals Drug Targets Against Common Fungus

Scientists have used single-particle cryogenic electron microscopy to determine the structure of the ribosome of Candida albicans. Their results reveal a potential target for new ...

Scientists Identify How the Brain Links Memories

Our brains lose the ability to link related memories as we age. Scientists genetically restored this brain function in middle-aged mice and identified an FDA-approved drug that achieves the same ...

New Insights Into Antibiotic Resistance

Treatment of severe infections caused by pathogenic bacteria relies on 'last resort' antibiotics, but rising resistance by 'superbugs' to most clinically approved drugs leaves ...

Nearly 108,000 Overdose Deaths in US in 2021

A grim prediction made half a decade ago by epidemiologists and modelers has come true: More than 100,000 people are now dying from drug overdoses annually in the ...

'Happy Hormone' Dopamine Plays Role in Identifying Emotions

Emotion-recognition among people with disorders such as Parkinson's disease or schizophrenia may be affected by changes in the levels dopamine in the brain, say ...

Research Boosts 'Game-Changing' Technology to Strengthen Drug Development

Researchers have boosted pioneering technology to show whether potential treatments are worth progressing into human trials, in a game-changing move that could dramatically reduce the high failure ...

Scientists Find Sea Corals Are Source of Sought-After 'Anti-Cancer' Compound

The bottom of the ocean is full of mysteries but scientists have recently uncovered one of its best-kept secrets. For 25 years, drug hunters have been searching for the source of a natural chemical ...

Research Brings Hope for Spinal Cord Injury Treatment

Scientists have shown an existing drug may reduce damage after spinal cord injury, by blocking the inflammatory response in the spinal ...

Repurposed Antibiotic May Be an Effective Therapeutic in COVID-19 Infected Mice

Repurposed drugs may have a speedier path to clinical use because they have already been shown to be safe in people. A new study suggests clofoctol may be an effective treatment for SARS-CoV-2 ...

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