June 15, 2022 — Researchers reveal a mechanism by which prostate cancer cells become resistant through molecular modification of the androgen receptor protein and identify a potential treatment approach that could ...
June 3, 2022 — Nearly 43% of patients with non-small cell lung cancer (NSCLC) whose lung cancers harbored a specific KRAS mutation responded to the experimental drug adagrasib, and the targeted agent also showed ...
June 3, 2022 — Researchers have identified potent, highly specific compounds that interfere with bromodomain (BD)-containing proteins involved in cancer. The compounds, called BET BD1-inhibitors, are a starting ...
June 3, 2022 — A team of public health modelers and substance use experts has developed a dynamic model based on national data from 1999 to 2020 that tracks the evolution of the opioid crisis for public policy ...
June 3, 2022 — Combination chemoimmunotherapy with the Bruton's tyrosine kinase (BTK) inhibitor ibrutinib demonstrated improved progression-free survival over standard chemoimmunotherapy for previously ...
June 2, 2022 — Mechanisms associated with a particular diabetes drug can also help to protect against Alzheimer's disease, a new study reports. The results indicate that the drug's target protein can be ...
June 2, 2022 — An investigation into the evolution of Salmonella bacteria infecting Brazilian poultry shows that the introduction of a Salmonella vaccine, combined with increasing antibiotic usage by Brazilian ...
May 31, 2022 — According to a new study, a new class of antibiotics is highly effective against drug-resistant tuberculosis. If validated in clinical trials, the new drug class would represent a major advance in ...
May 26, 2022 — A synthesized antibiotic derived from computer models of bacterial gene products appears to neutralize even drug-resistant bacteria. The compound, named cilagicin, works well in mice and employs a ...
May 26, 2022 — Hypertension, or high blood pressure, is a major risk factor for heart disease and stroke, two of the leading causes of death in America. It's also one of the most common chronic conditions in ...
May 26, 2022 — Once a state legalizes recreational cannabis and increase in youth using it illegally occurs, report ...
May 25, 2022 — Scientists have used single-particle cryogenic electron microscopy to determine the structure of the ribosome of Candida albicans. Their results reveal a potential target for new ...
May 25, 2022 — Our brains lose the ability to link related memories as we age. Scientists genetically restored this brain function in middle-aged mice and identified an FDA-approved drug that achieves the same ...
May 25, 2022 — Treatment of severe infections caused by pathogenic bacteria relies on 'last resort' antibiotics, but rising resistance by 'superbugs' to most clinically approved drugs leaves ...
May 25, 2022 — A grim prediction made half a decade ago by epidemiologists and modelers has come true: More than 100,000 people are now dying from drug overdoses annually in the ...
May 24, 2022 — Emotion-recognition among people with disorders such as Parkinson's disease or schizophrenia may be affected by changes in the levels dopamine in the brain, say ...
May 24, 2022 — Researchers have boosted pioneering technology to show whether potential treatments are worth progressing into human trials, in a game-changing move that could dramatically reduce the high failure ...
May 23, 2022 — The bottom of the ocean is full of mysteries but scientists have recently uncovered one of its best-kept secrets. For 25 years, drug hunters have been searching for the source of a natural chemical ...
May 20, 2022 — Scientists have shown an existing drug may reduce damage after spinal cord injury, by blocking the inflammatory response in the spinal ...
May 19, 2022 — Repurposed drugs may have a speedier path to clinical use because they have already been shown to be safe in people. A new study suggests clofoctol may be an effective treatment for SARS-CoV-2 ...